CBD or cannabidiol is one of the hundreds of compounds found in cannabis that belongs to a class of cannabinoids. CBD is a non-psychoactive substance, despite it being a component of cannabis, which is why anybody can use it. Let’s take a look at the benefits of CBD oil in details.
The Proven Benefits of CBD
Treatment of ADD/ADHD
The severity of the ADD/ADHD symptoms is correlated with low dopamine and high cortisol levels, both of which can be regulated with CBD. [1] The substance lower the cortisol and increase the dopamine levels, making it one of the most effective medications for treating the conditions. While the number of supporting studies are still relatively low, there is plenty of anecdotal evidence which supports the claim.
Relieves Pain and Inflammation
CBD has been proven time and again to reduce pain and inflammation, and it’s one of the main reasons why people use it. [2] Many research has found that CBD is effective at reducing the pain felt by patients. [3] It works by inhibiting the neural transmission from the pain receptors.
The anti-inflammatory property is also another benefit of CBD. The Journal of Experimental Medicine published a study in 2012 that found that CBD suppressed the inflammatory and neuropathic pain in mice without causing analgesic tolerance. [4]
Antipsychotic Effects
There have been a number of studies which found that CBD has antipsychotic properties. It’s also been found that the substance can prevent psychosis. This makes it incredibly useful for treating mental illnesses that cause hallucinations like schizophrenia. [5]
Reduces Anxiety
Another one of the most proven benefits of CBD is for reducing anxiety. It soothes the symptoms, which help to calm down a patient with severe anxiety disorder. It’s also been found to help ease panic attacks, OCD and PTSD. [6]
Fights Cancer
While it’s still being debated whether the effect is real, but a number of published research to halt the migration, adhesion and invasion of the cancer cells. The Journal of Pharmacology and Experimental Therapeutics found that CBD showed significant inhibition of the cell growth of breast tumours without harming regular cells. [7]
More and more studies have found similar effects in other forms of cancer cells. As more effort is put into studying the full effect of CBD, the future of a treatment for cancer is looking better with each year.
Relieves Nausea
The British Journal of Pharmacology published a study in 2012 which suggests that CBD is highly effective at relieving nausea. It was reported in the same study that the substance also has anti-emetic effects on rats as well. [8]
Treats Epileptic Seizures
In a 2014 study published by Standford University, it was reported that when compared to other anti-epileptic medicines, CBD was significantly more effective at treating epileptic seizures. [9] It’s also been found to help increasing alertness, awareness as well as improving mood and sleep.
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References:
1. Cooper, R.e., et al. “Cannabinoids in Attention-Deficit/Hyperactivity Disorder: a Randomised-Controlled Trial.” European Neuropsychopharmacology, vol. 26, 2016, doi:10.1016/s0924-977x(16)30912-9.
2. Hammell, D.c., et al. “Transdermal Cannabidiol Reduces Inflammation and Pain-Related Behaviours in a Rat Model of Arthritis.” European Journal of Pain, vol. 20, no. 6, 2015, pp. 936–948., doi:10.1002/ejp.818.
3. Elikottil, Mbbs Jaseena, et al. “The Analgesic Potential of Cannabinoids.” Journal of Opioid Management, vol. 5, no. 6, 2018, p. 341., doi:10.5055/jom.2009.0034.
4. Xiong, Wei, et al. “Cannabinoids Suppress Inflammatory and Neuropathic Pain by Targeting α3 Glycine Receptors.” The Journal of Experimental Medicine, vol. 209, no. 6, 2012, pp. 1121–1134., doi:10.1084/jem.20120242.
5. Bhattacharyya, Sagnik, et al. “Effect of Cannabidiol on Medial Temporal, Midbrain, and Striatal Dysfunction in People at Clinical High Risk of Psychosis.” JAMA Psychiatry, vol. 75, no. 11, 2018, p. 1107., doi:10.1001/jamapsychiatry.2018.2309.
6. Blessing, Esther M., et al. “Cannabidiol as a Potential Treatment for Anxiety Disorders.” Neurotherapeutics, vol. 12, no. 4, 2015, pp. 825–836., doi:10.1007/s13311-015-0387-1.
7. Ligresti, A. “Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma.” Journal of Pharmacology and Experimental Therapeutics, vol. 318, no. 3, 2006, pp. 1375–1387., doi:10.1124/jpet.106.105247.
8. Parker, Linda A, et al. “Regulation of Nausea and Vomiting by Cannabinoids.” British Journal of Pharmacology, vol. 163, no. 7, 2011, pp. 1411–1422., doi:10.1111/j.1476-5381.2010.01176.x.
9. Porter, Brenda E., and Catherine Jacobson. “Report of a Parent Survey of Cannabidiol-Enriched Cannabis Use in Pediatric Treatment-Resistant Epilepsy.” Epilepsy & Behavior, vol. 29, no. 3, 2013, pp. 574–577., doi:10.1016/j.yebeh.2013.08.037.